Abstract:Hydatid disease or Echinococcosis is caused by the consumption of food contaminated by canine faeces. The incidence of hydatid disease in pregnancy ranges from 1in 20,000 to 1 in 30,000. The most common site of hydatid cysts is the liver. The diagnosis of liver hydatid cysts is not difficult but the management poses problems more particularly during pregnancy. Both medical and surgical treatments are available but there is no consensus and each case has to be individualized. We present a case of hydatid cyst of liver diagnosed during pregnancy which was managed by strict monitoring and albendazole therapy.

The success of a Raman spectroscopy device in cancer detection lies in its ability to acquire high-quality Raman signals from samples and to employ efficient classification algorithms in analysing spectral data. Portable Raman systems enabled with artificial intelligence tools are well adaptable to clinical settings and for accuracy for community-level rapid screening. Here, we developed a robotic Raman device with a high-efficiency Raman probe, validating it against endometrial cancers detecting high-grade, low-grade cancers and normal classes. Algorithms like principal component analysis-discriminant analysis, and support vector machine were compared against the deep learning methodology; convolutional neural network (CNN) with and without data augmentation. Eventually, the system could classify high-grade, low-grade and normal tissues with an F1-score of 91%, 94% and 97%, respectively. CNN with data augmentation proved to be the most dependable classifier that works well even in the presence of high background noise. Thus, we demonstrate a unique portable Raman device with AI tools for high-sensitivity Raman analysis of endometrial cancer.

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The synchronous endometrial and ovarian cancer is a rare phenomenon with incidence of 1.4 to 3.8%. Mostly in SEOC, the ovarian endometroid carcinoma arises in background of endometriosis with endometrial carcinoma with lower stage and lower grade in premenopausal age group. Case report: We are reporting a case report of Synchronous type 2 endometrial and ovarian cancer \ with an unusual presentation at later age of 70, in postmenopausal lady with higher grade of endometrial carcinoma and higher stage of ovarian cancer and patient was treated with adjuvant chemotherapy followed by vault brachytherapy in view of Stage II B ovarian cancer and IA grade 3 endometrial cancer. Conclusion:The SEOC being a rare phenomenon with different therapeutic and prognostic considerations, and hence can be managed with multidisciplinary approach and regular follow up.

Endometrial stromal sarcomas are the rare tumor accounting for <2% of all uterine tumor. It is diagnosed mostly in 40-55 years age with slow growth with extrauterine spread in 40-50% of the cases at the time of diagnosis. In this case report, ESS was diagnosed in a 40 year old lady with pulmonary and cardiac metastasis surgically managed followed by adjuvant hormonal treatment with local recurrence treated with radiotherapy with good prognosis. ESS with distant metastasis can have better prognosis if treated surgically with complete resection and adjuvant therapy with multidisciplinary approach and regular follow up.