Ti6Al4V titanium alloy is considered a biocompatible material, suitable to be used for manufacturing medical devices, particularly cranioplasty plates. Several methods for processing titanium alloys are reported in the literature, each one presenting both advantages and drawbacks. A decision-making method based upon AHP (analytic hierarchy process) was used in this paper for choosing the most recommended manufacturing process among some alternatives. The result of AHP indicated that single-point incremental forming (SPIF) at room temperature could be considered the best approach when manufacturing medical devices. However, Ti6Al4V titanium alloy is known as a low-plasticity material when subjected to plastic deformation at room temperature, so special measures had to be taken. The experimental results of processing parts from Ti6Al4V titanium alloy by means of SPIF and technological aspects are considered.

Open spina bifida, also known as spina bifida aperta is a neural tube defect involving the lack of closure of vertebral arches and associated meninges and/or spinal cord abnormalities.Ultrasound examination is the gold standard for the diagnosis of spina bifida aperta. It represents the main imaging tool used to ascertain this diagnosis early in gestation. Three-dimensional ultrasound is necessary to detect the level and the size of the defect. Magnetic resonance imaging (MRI) represents a more sensitive tool, giving specific information of the defect and associated anomalies, playing an important role in ruling out differential diagnosis. Due to the advent of MRI use, it is possible today to achieve in utero treatment of fetuses with this pathology. The aim of the current review is to provide an update of literature regarding the role of ultrasound and MRI in the prenatal diagnosis of spina bifida aperta.

Synthetic polypropylene materials are increasingly being used in surgery to repair parietal defects in perineal floor curing surgery, in genital prolapse and stress urinary incontinence. The tissue response to contact with these materials varies, and the inflammatory tissue response may be a prognostic marker of success in surgical interventions that involve contact between tissues and polypropylene materials.

Since the time of their introduction into medical practice, biomesh were criticized for their lack of tissue integration and the rejection due to the organism reaction for an element that is not autologous. The mechanisms by which these changes of contact between the tissue and the foreign material were produced were initially incompletely understood, but over time the involvement of the immune system mediated by the cellular or humoral local inflammatory reaction was established.

This paper presents some experimental researches regarding the manufacturing accuracy of a profiling machine together with an approach to eliminate the positioning and contouring errors. A mathematical model based on transfer functions is used as starting approach in order to tune the feed drives of the machine. The accuracy of the profiling machine is tested before and after the tuning process, in order to validate the proposed approach. There are unfolded both positioning tests along one axis and contouring tests on two axes.