The self-aggregation of sodium dodecyl benzene sulfonate (SDBS) and its solution behaviors have been critically assessed by conductometric, tensiometric, spectrophotometric, flourimetric, and calorimetric methods. The interfacial adsorption behaviors of SDBS have also been assessed critically. Based on the isothermal titration calorimetric (ITC) measurements, the thermodynamics of micellization of SDBS have been examined in the light of both "mass action" and "pseudophase" principles. A method of simulation has been used to evaluate the aggregation number and the free energy of micellization according to the mass action model. The thermodynamic parameters derived indirectly from the rationale of van't Hoff and directly by microcalorimetry have been compared and discussed. The interaction of SDBS with the water-soluble polymers poly(vinyl pyrrolidone) (PVP), the chloride salt of the N,N-dimethyl-N-methyl derivative of hydroxyethylcellulose (JR 400), and the chloride salt of the N,N-dimethyl-N-dodecyl derivative of hydroxyethylcellulose (LM 200) have been also investigated by the conductometric and microcalorimetric methods. The critical aggregation concentration (cac) and the thermodynamics of binding of the aggregates with the polymer segments, as well as the thermodynamics of formation of free micelles in solution, in the presence of PVP, JR 400, and LM 200 have been quantitatively assessed.