Dengue hemorrhagic fever (DHF) is a disease caused by dengue virus infection. One symptom of dengue virus infection is high fever and headache. Dengue virus is a virus from the genus Flavivirus, family of Flaviviridae. This dengue fever is a dangerous viral disease because it can cause sufferers to die in a very short time / several days. The existence and population density are often associated with transmission, endemicity and Extraordinary Events (EE) of DHF. Disease mapping by utilizing digital technology to support epidemiological investigations and also as a tool to monitor regional conditions for dengue disease. The purpose of this study was to determine efforts to prevent and control dengue disease by mapping. The results of the study show that mapping can be seen as increasing and decreasing the number of cases of dengue disease so that it can assist in data management and reporting of information to monitor areas at risk of contracting dengue disease. Suggestions given need to do further research using other variables that are the cause of the high rate of dengue cases, so that it can be utilized by related agencies as the basis of the information system supporting the decision on preventive measures to combat dengue.

Abstract. Menstrual cycle is a naturally occurring mechanism in a reproductive aged woman. The ability of a woman to identify the length of a menstrual cycle is important as a basis to determine the fertile period in the subsequent menstrual cycle. This research aimed to investigate the length of menstrual cycle of women in reproductive age. A regular menstrual cycle occurs in a regular pattern of length which can range from 21 to 35 days in adults. A subsequent cycle which occurs three to five days earlier or longer than the usual pattern would still be considered as normal. Meanwhile, a menstrual cycle which occurs twice in a month or once in more than two months would be considered as irregular cycle. The method implemented was an exploratory method through which menstruation periods of woman in reproductive age were recorded in three consecutive months. The research population was Biology students who are registered in academic year 2017. The participants were students who are registered in Reproduction and Animal Development subject. The data of menstrual period were collected from four study group which consists of 101 students. The result of data analysis on a total of 171 menstrual cycle showed that the average length of participants' menstrual cycle was 30.08 days. The total of participants showed regular and irregular length of menstrual cycle was 59.41% and 42.57% respectively.

The experimental design in this study was used to optimize the results of extracting pectin from kepok banana peels by surface method. The model for predicting and optimizing the process of extracting kepok banana pectin consists of 4 axillary points, 4 factorial points, and 5 middle titlication replications using a central commision design (CCD) with DX6.0.4 software. The independent variables used in the optimization of the extraction results of kepok banana pectin are pH and temperature, where the pH is between 1.5 - 2.5 and temperatures are 60°C-100°C and the combination of independent and bound variables (extraction time). The results of pectin extract ranged from 5.79% to 22.57% (b / b, based on the dry weight of kepok banana peel). The variables of pH and temperature, the interaction between pH and temperature, and the interaction between extraction time and pH significantly influence. The optimum conditions for extraction of pectin are estimated at pH (2.5) and temperature (100°C). In optimal conditions, the actual pectin yield is 22.57%, which is below the estimated extraction condition of 21.286%. Analysis of variance, adj R2 and R2, model lack of fit test, and p value statistically indicate that the model is adequate in representing experimental data. The effect of pH and extraction temperature was very significant (P <0.001) on the extraction results of kepok banana peel pectin. This shows that these two variables are very important in the process of extracting kepok banana peel, where the R2 value is 96.01%.

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This research aimed to develop natural family extension media online which can be used as alternative method of family planning, to know the effectiveness of natural family planning extension media online, and to give knowledge of reproductive health in women. The development of Natural Family Planning media using the 4-D development model developed by S. Thiagarajan, Dorothy S. Semmel, and Melvyn I. Semmel includes: Define, Design, Develop and Disseminate. Stage Develop, producing revitalized Natural Algorithm on line media based on input from experts and on-line instruments to get a knowledge of family planning and reproduction health. Furthermore, the dissemination (Disseminate). At this stage is use of Natural Family Planning extension of media online/off line that has been developed on a wider scale to conduct Natural Family Planning online/offline. Results obtained 1) Natural Family Planning media online/offline in the form of PPT Media, Video, Quiz and Forum Valid, 2) Media Extension effectively used by family planning officer of online, 3) Natural Family Planning improved female reproductive health.