The purpose of this study was to design a suitable mobile application for high mobility medical staff to support the health referral system of Indonesian universal health coverage. Methods: Design science research (DSR) approach were conducted with two iterations. The first iteration was conducted by designing a high-fidelity mockup and evaluating the design using the System Usability Scale (SUS) framework to evaluate the overall usability of the system (n ¼ 48). The second iteration was conducted by designing a running prototype and evaluating the design using the Post-Study System Usability Questionnaire (PSSUQ) framework to evaluate the system's usefulness, information quality, and interface quality (n ¼ 31). For designing the user interface, the eight golden rules guided the process. Results: The results found that the design for the first iteration was good and the second iteration's design was satisfactory to the respondents. The information quality aspects underwent several changes such as the implementation of local language as the users deemed it to be important to help them easily understand and use the system and eventually support their mobility at the health facility.