RESUMO.As lesões no miocárdio são de difícil diagnóstico e podem ser confundidas com outras enfermidades, portanto é importante a associação de diferentes métodos de diagnósticos para a conclusão. Na medicina humana as troponinas são reconhecidas, há vários anos, como biomarcadores sensíveis e específicos na identificação de lesões miocárdica. As troponinas são expressas exclusivamente pelo miocárdio e liberadas para circulação logo após uma injúria no músculo cardíaco. Essa revisão aborda os diferentes tipos de troponinas, dando enfoque a sua aplicabilidade e comportamento como marcador de lesão tecidual em animais. Constatou-se se que o uso da troponina I cardíaca (cTnI), como biomarcador de injuria cardíaca, foi validada para o uso diagnóstico em diferentes espécies animais e é capaz de colaborar no diagnóstico e prognóstico das enfermidades miocárdicas, embora, não determinem o mecanismo da lesão. Palavras chave. Animais, biomarcadores, cTnI, isoformas cardíacas, miocárdioTroponin, a cardiac injury biomarker, in veterinary medicine: Review ABSTRACT. Lesions in the myocardium are difficult to diagnose and can be confused with other illnesses, so it is important to combine several diagnostic methods for accuracy. In human medicine, troponins have been recognized for several years as sensitive and specific biomarkers for the identification of myocardial injury. Troponins are exclusively expressed by cardiac myocytes and released into the circulation after an injury to the heart muscle. This review different types of troponins, focusing on their applicability and behavior as a marker of cardiac injury in animals. It was found that the use of cardiac troponin I (cTnI) as a biomarker of cardiac injury has been validated for diagnostic use in several animal species and can assist in diagnosis and prognostication of myocardial diseases though, but does not specify the mechanism of injury.
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