Introduction and Aims: Patients after kidney transplantation experience rapid bone mass loss in the early post transplant period resulting in high fracture rate in this population. In the later period bone density stabilize but data about this are sparse. We conducted this analysis to determine bone mineral density (BMD) during the first five post transplant years. Methods: This is a retrospective clinical study. One hundred twenty-eight patients, 67 males, 61 females, with mean age 45 ± 11 years (17 to 64 years) with kidney graft transplanted in UMC Ljubljana were included in the study. All recipients were on quadriple immunosuppression with IL2 receptor blocker, methylprednisolone, cyclosporine and mycophenolate. Their BMD measurements of lumbar spine and hip were routinely performed by dual X-ray absorptiometry at the time of transplantation and after 1, 3 and 5 years. Laboratory parameters were followed at regular clinic visits. Results: At the time of transplantation 40.2% of patients had BMD in the range of