Resuscitation or death occurred in 6% of cases. Any associated risk factors could not be determined because the number of complications was too small. Risks may be highest in children with severe idiopathic PHT and symptoms of chest pain, syncope, or dizziness.
SummaryOxygen levels (tension, saturation, and content) in blood from varicose leg veins were found to be significantly lower than those in blood from normal leg Paroven, the product used, is a mixture mainly of mono-, di-, tri-, and tetra-O-(3-hydroxyethyl) rutosides containing not less than 45% troxerutin, the approved name of the principle compound tri-O-(/3-hydroxyethyl) rutoside. Hydroxyethylrutosides have been reported to relieve leg symptoms associated with varicose veins (Fitzgerald, 1967;Allen, 1970;Rose, 1970) and to accelerate healing of varicose ulcers (Ghittoni and Martini, 1967). The precise mode of action of hydroxyethylrutosides when tissue microcirculation is embarrassed by venous stasis and venous hypertension is uncertain, but experimental studies indicated that its principal effect is on capillary and venule function and that it is not a vasodilator. Enhanced capillary resistance (Foelsche, 1968), reduced capillary permeability (Harrison, 1967), reduction of oedema (Fabre and Rudhardt, 1962), and augmented venous return (Pfister and Lindner, 1967)
SUMMARY
A case of spontaneous pyelo‐duodenal fistula is described and is the twenty‐fourth so far recorded in the Iiterature. It is the first case to have survived without surgical ablation of the fistula immediately following the diagnosis.
The symptomatology and treatment of the condition are briefly reviewed. Ail previously reported cases are listed in table form to correlate the setiology, management and prognosis. Analysis of the cases suggests that although definitive surgery is the treatment of choice, a more critical evaluation of the rationale is now required. Antibiotic therapy has removed tuberculosis from the aetiology and the prognosis for the non‐malignant pyelo‐duodenal fistula is excellent.
Acute hind‐limb ischaemia was produced in anaesthetized, ventilated dogs. During ischaemia the femoral venous oxygen tension fell markedly and both oxygen extraction and consumption appeared to increase. Oxygen at 2 ATA produced a relatively small increase in oxygen availability to the ischaemic tissues; femoral venous oxygen tension rose by 20 mm. Hg but oxygen extraction and consumption remained elevated.
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