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A Gender Identity Project was established to study people who present with the chief complaint of transsexualism. A multidisciplinary approach was chosen and patients were investigated from the genetic, neuroendocrinological, psychological, and social aspects. The organization of the project and the protocol for evaluation of the patients are outlined. The investigators hope that almost all cases seen for evaluation, including those who dropped out and those who have been rejected in the process, will be seen for follow-up and that this will provide some indication of how to help these people. The findings of the study, together with reports on the studies which arose as extensions of the original investigation, will be reported in subsequent publications.

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