A survey of directors of pharmacy revealed that labor costs and the time required to manage drug shortages are significant and that current information available to manage drug shortages is considered suboptimal.
Vapor−liquid−liquid equilibrium data for the binary systems 2-methyl-1,3-dioxolane + water and 2,4-dimethyl-1,3-dioxolane + water were collected by using a modified Othmer still vessel at 1 atm of pressure.
The UNIQUAC equation of state was fitted to the experimental T−x−x−y data to generate the coefficients
of the binary interaction parameters for each system. Vapor pressures for pure 2,4-dimethyl-1,3-dioxolane
and 2-methyl-1,3-dioxolane were also measured and used to calculate the constants in Antoine's equation
and pure component parameters for each dioxolane. The enthalpy of vaporization calculated from vapor
pressure data via the Clausius−Clapeyron equation was in good agreement with the literature value.
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