The use of latrines by the community will affect the incidence of ducts, such as diarrhea. The Karanganyar Regency Government has built communal latrines to reduce open defecation, however is not yet optimal and there are still many open defecation communities (BABS). This study aims to examine the determinants of latrine utilization by the community. Observational research has been carried out with Cross-Sectional design. A total of 83 family heads from 578 populations were taken by proportional random sampling as research subjects. The variables examined in this study include knowledge, attitudes, latrine ownership, availability of clean water, support from community leaders and health workers, and latrine utilization. Data collection is done by interview and direct observation of research objects, with questionnaire instruments and observation sheets. Research data were analyzed by Chi-Square Test. As many as 18.1% of the people do not use latrines to defecate. Statistical analysis showed that there was a relationship between attitudes, latrine ownership, availability of clean water, and support from community leaders with the practice of using latrines in daily bowel movements with p-values of < 0.05, respectively. This research concludes that the attitude of the community, latrine ownership, availability of clean water, and community support greatly influenced the practice of using latrines for defecation.