Rhodomyrtus tomentosa (Ait.) Hassk is a fruit that is gradually becoming popular in Vietnam with superior bioactive compounds. This study aimed to determine the natural anthocyanins from Rhodomyrtus tomentosa (Ait.) Hassk based on extracts and optimized RSM. The Box-Behnken design was shown the influence of the optimal conditions for the MAE procedure are 5.07 min, 206 W and 2.53 g/mL with the optimal anthocyanin content achieved Y = 133.88 mg/L, all reactions are within the threshold of the predicted value. The results are in line with the proposed model for the anthocyanin extraction (R2 = 0.9849).

Anthocyanins are naturally occurring polyphenols that plays an essential role in the prevention and treatment of cancer, eye diseases, and so on. This study aimed to determine the natural anthocyanins from violet glutinous rice grown in Phu Tho province, Vietnam based on its extracts and optimize the process with response surface methodology (RSM). Four experimental parameters including the material-solvent ratio (g/mL), time (minutes) and microwave power (W) was selected for optimization. The maximum yield of anthocyanin was 1,385 mg/g, achieved at conditions of material-to-solvent ratio of 10.29 g/mL, a time of 4.4 min, and a microwave power of 90.54W. The established RSM model showed relative good fit with the experimental data regarding the anthocyanin extraction process (R2= 0.988).

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