A series of triterpene endoperoxides was synthesized and screened for antitumor activity in a panel of 15 human cancer cell lines by a sulforhodamine-B (SRB) assay. The compounds induce apoptosis and show excellent antitumor activity.
Defensive secretions of adult and larval Suocerathrips linguis (Phlaeothripidae, Thysanoptera) were found to contain a long-chained acetate, (11Z)-11,19-eicosadienyl acetate, that was not previously known to occur naturally. This substance occurred together with octadecyl acetate and other long-chained acetates. The eicosadienyl acetate repels ants and spreads on the surface of such potential predators. The mixture can provide a long-lasting surface coating.
Synthesis and Biological Evaluation of a "Natural" Insect Repellent -[strategies for the synthesis of the efficient ant repellent (I) and its (E)-isomer, which does not exhibit any repellent activity]. -(CSUK*, R.; NIESEN, A.; Z. Naturforsch., B: Chem. Sci. 59 (2004) 8, 934-942; Inst. Org. Chem., Martin-Luther-Univ. Halle-Wittenberg, D-06120 Halle/S., Germany; Eng.) -Koehler 49-211
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