Introduction: Genital malignancies in women varies widely from developed to developing countries. Postmenopausal women are at risk of developing various genital malignancies.

Red degeneration of leiomyoma is a rare type of degeneration. Hyaline, calcareous, and fatty degenerations are being more common. It is a medical enigma because of its peculiar and acute presentation associated with pregnancy. Red degeneration of fibroid is very rare in nonpregnant women. Although uncommon, a gynecologist should be aware of the entity for timely diagnosis and treatment. Here two cases of red degeneration in nonpregnant women are reported. In the first case, a woman was reported with menorrhagia, fever, pain, and urinary complaints. Red degeneration of fibroid was not suspected and, to utter surprise, the histopathology report was suggestive of red degeneration of fibroid. In the second case, a woman was presented with a lump and pain in the abdomen, and history of fever. On the basis of the previous experience, clinical diagnosis of red degeneration was considered. It was confirmed by histopathology.

Verrucous carcinoma of the vulva is a rare variant of squamous cell carcinoma, with about 50 cases reported in the literature. We report a 38-year-old patient with verrucous carcinoma of the vulva.