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AIMTo determine the incidence of female Genital Tuberculosis (GTB) and to analyse clinicopathological features for GTB and comparison of Polymerase Chain Reaction (PCR), Acid Fast Bacillus (AFB) staining and Histopathology (HPR). STUDY SETTINGA prospective study conducted on 50 infertile patients in the Department of Obstetrics and Gynaecology at Krishna Hospital, Karad, for a period of 2 years between December 2013 and December 2015. METHODSPatients were investigated for the presence of Mycobacterium Tuberculosis (MTB) on samples collected by endometrial curettage by PCR, AFB and HPR. Additional tests like Hysterosalpingography (HSG) Laparoscopic chromopertubation and hysteroscopy were performed if not done earlier. RESULTPCR demonstrated MTB DNA in 9 patients, and 2 were positive with AFB and HPR. Within positive patients HSG findings were suggestive of TB in 3 cases and laparoscopy in 5 cases and hysteroscopy in 4 cases. Two MTB PCR positive patients conceived spontaneously after 6 months of anti-tubercular treatment.