Mastocytosis occurs due to clonal, neoplastic proliferation of mast cells that accumulate in one or more organ systems. It is characterized by an abnormal mast cell infiltrates1 . It can be divided into cutaneous and systemic Mastocytosis. Mast cell infiltrates remain confined to skin in cutaneous Mastocytosis. Urticaria pigmentosa / Maculopapular cutaneous Mastocytosis , Diffuse cutaneous Mastocytosis and mastocytoma of skin are the 3 variants of cutaneous Mastocytosis. Systemic mastocytosis is characterized by the involvement of atleast one extracutaneous organ with or without evidence of skin lesions. This paper describes 3 cases of paediatric cutaneous mastocytosis.
Rhabdomyosarcoma is a malignant mesenchymal tumor with skeletal muscle differentiation. It is the most common soft tissue sarcoma in children and adolescents. Its incidence is 4.5 cases per 1 million people aged 0-20 year. Embryonal, alveolar, pleomorphic and sclerosing /spindle cell types are the major variants of rhabdomyosarcoma. Embryonal rhabdomyosarcoma is the most common type. Rhabdomyosarcoma is highly aggressive and usually patient presented with pressure symptoms or metastasis. We are reporting 2 cases of rhabdomyosarcoma with one patient presented with abdominal wall nodules and other patient with bilateral breast lumps.
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