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The 2-aminoethyl glycoside of 0 -a-L-f u cop yr anos y 1-(1 + 2 ) -0 -p -Dgalactopyranosyl-( 1+3)-[ O-a-L-fucopyranosyl-( 1+4)]-2-acetamido-2-deoxy-p-Dglucopyranose (Lewis B tetrasaccharide) was synthesized on a large scale and acryloylated with acryloyl chloride. The obtained oligosaccharide 2-acrylamidoethyl glycoside was then copolymerized with acrylamide to form a water-soluble, high molecular weight polymer, suitable for use in adhesion inhibition studies with HeZicobacter pylori. Also synthesized were the corresponding derivatives of 0 -a-L-f ucop yr anosyl-( 1 -+ 2)-0-p-D-gal a c topyranosyl-(l+3)-2-acetamido-2-deoxy-p-D-glucopyranose and O-a-L-fucopyranosyl-( 1+2)-p-D-galactopyranose.

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