International audienceMetropolization, namely the concentration of households and activity in the more developped cities, leads to greater spatial differentiation and specialization in the urban area, generating new flows and new urban dysfunctions. Although distance to the centre is still relevant to understand the location of economic activities, a spatial analysis of the location of the establishments in the urban area of Lyon highlights the emergence of peripheral employment poles, the most attractive and diversified of which suggest that a shift towards a multi-functional polycentric urban organization is taking place.La métropolisation, concentration des populations et des activités dans les plus grandes villes, conduit à une différenciation spatiale et une spécialisation croissante des agglomérations urbaines, qui génèrent de nouveaux flux et de nouveaux dysfonctionnements. Bien que la distance au centre structure encore largement les localisations, une analyse spatiale de la répartition des établissements dans la métropole lyonnaise met en évidence l’émergence de pôles d’emploi périphériques, dont les plus attractifs et diversifiés suggèrent l’apparition d’une organisation urbaine polycentrique multi fonctionnelle
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