Based on these results, serum cTnI appears to be a valuable predictive marker of cardiovascular events in asymptomatic dialysis patients. For those patients who might benefit from thorough cardiac investigation and treatment, information on cTnI could be useful in preventing cardiac events.

The effects of age, sex, pregnancy, were analyzed and data from fasted and fed animals were compared in a population of cynomolgus macaques. No significant sex effects were observed for biochemical values and no changes were found in male hematological parameters in relation to age. Most values of females during pregnancy were within normal ranges. Comparison between fed and fasted animals showed that several biochemical parameters (e.g., ALT, glucose, CPK, LDH) and several hematological parameters (e.g., monocytes, eosinophils, basophils, hemoglobin, MCV, MCHC, and MCH) were affected by food intake.

An increase in solute removal, a shorter dialysis session, the patient's well being and the reduction of global costs are the principal aims of the new hemodialysis methods. The simultaneous use of two hemodialyzers in hemodialysis has been experimented by other researchers. Our technique involves the use of two cuprophan hemodialyzers in sequence (double filter system: DFS), each one connected separately to fresh dialysate. Fifteen symptomatic large patients were treated with DFS and the results were compared to conventional hemodialysis (CHD). After the first hemodialyzer, modification of pH and electrolytes occurred in the plasma composition. In the second hemodialyzer, urea depuration occurred without further significant changes in hydroelectrolytic or acid-basic plasma patterns. The Kt/V increased from 1.10 to 1.29 (18%). The authors conclude that in DFS there was an advantage in urea clearance, osmolarity stability and reduction of side effects.

Background/Aims: The principal aims of the new hemodialysis methods are: a short-time dialysis session, the increase of solute removal, the patient’s well-being and, when possible, the reduction of global costs. Other researchers have experimented the simultaneous use of two hemodialyzers in hemodialysis. We tested a new technique which involves the use of two Cuprophan hemodialyzers in sequence (double filter system: DFS), each one connected separately to fresh dialysate. Methods: We treated 15 large patients with DFS and compared the results with conventional hemodialysis (CHD). Results: Our results showed a significant difference between CHD and DFS in the depuration values. After the first hemodialyzer, modification of pH and electrolytes occurred in the plasma composition. In the second hemodialyzer, urea depuration occured without further significant changes in hydroelectrolytic and acid-basic plasma patterns. The Kt/V increased from 1.10 to 1.29 (18%). Conclusion: Our technique is conceived for the following goal: to increase the diffusion of solution without increasing costs and side effects.

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