No abstract

The composition of biologically active substances of aqueous extracts of couch grass was studied and the following groups of biologically active substances were identified: coumarins, iridoids, saponins, slimes, polysaccharides (including inulin), ascorbic acid and b-carotene, flavonoids (rutin, hyperoside, baicaleine) phenocarboxylic acids (chlorogenic and p-hydroxycinnamic acids), and tannins. The effects of couch grass extract in the form of a cream on several measures of lipid peroxidation in allergic contact dermatitis were studied in experimental conditions. Cream containing couch grass extract was found to have normalizing actions on measures of lipid peroxidation (diene conjugates, malondialdehyde, catalase) in the plasma of experimental animals.

The purpose of the research was studying influence of the ointment containing as the operating component an Empetrum black extract on some parameters of lipid peroxidation (diene conjugates, malonic dialdehyde, catalase) at allergic contact dermatitis at rats in plasma of blood and leather. As a result of experiment on model of allergic contact dermatitis it is established, that ointment with an Empetrum extract normalizes processes of the lipid peroxidation (level malonic dialdehyde, diene conjugates and catalase did not differ from the control), that in turn, apparently, can also improve therapeutic effect (initial parameters of an integument were restored). While using the ointment with an Empetrum extract terms of recover of animals are reduced to 4—5 days in comparison with a group of incurable rats, but at the same time it concedes a little to hormonal «Akriderm SK».