The article defines the structural specifics of the scientific periodicals of the Kazan Physicians Society, characterizes the logic of its evolution, shows its place in the development of the general logic of qualitative changes in the methods of constructing and manifesting medical knowledge broadcast on its pages. The stages of the evolutionary transformation of the Diaries of the Physicians Society, which were the printed organ of the Physicians Society at the Imperial Kazan University, into a special edition the Kazan Medical Journal are analyzed in detail, the date of its official approval as a printed organ is specified. Based on the materials of the State Archives of the Republic of Tatarstan, many of which were not previously introduced into scientific circulation, the succession of the development of scientific periodicals was demonstrated, which makes it possible to reasonably indicate 1872 as the year when the Kazan Medical Journal started to be published. The article gives a brief description of the published volumes of this stage of the transformation of the Diaries of the Physicians Society, indicates the specifics of their formal, as well as content and, in particular, intertextual structure. The role and place of various types of published materials, such as original scientific articles, abstracts of current scientific literature of that time, annual literature reviews in various medical specialties, meeting reports of representatives of scientific societies, reports of medical congresses and the so-called doctoral disputes at Kazan University at that time, reports of practical health care institutions of Kazan, special correspondence, reviews of scientific works, scientific bibliography, were determined. An analysis of these elements evolution in the content of scientific periodicals made it possible to substantiate the logical model of the structural transformation of this printed organ as a special type of historical source, to determine the forms of its cultural and communicative functioning, to indicate its role in the development of the professional culture of the medical corporation of Kazan University and the city of Kazan.

The article is devoted to the study of the prerequisites and circumstances of the first trachomatous institute establishment in Russia, designed to stop the spread of a dangerous infectious eye disease in one of the key regions of the RSFSR the Republic of Tatarstan. The initial period of the spread of trachoma in the Russian Empire, dating back to the first quarter of the 19th century, is characterized, and the first steps in the study and treatment of trachoma in the Kazan province are defined. On the basis of archival documents, many of which were not previously introduced into scientific circulation, the authors analyze a significant layer of historical information that sheds light on a number of facts that have not been previously published or studied. The prerequisites that characterize the formation of the attitude of the Kazan scientific community to the need to organize the fight against a new spreading disease trachoma on a large scale, have been identified. For the first time, prosopographic data on the first leaders of the institute were clarified, it was convincingly proved that, contrary to popular belief, it was not V.V.Chirkovsky, but A.G.Agababov who became the first director of the Trachomatous Institute in Kazan. Materials on the circumstances and conditions of the actual opening of the trachomatous institute in 1922 are given. The features of the fight against trachoma in the period preceding the opening of the trachomatous institute, starting with the activities of E.V.Adamyuk, representatives of the Kazan Governorate and special medical commissions, ending with the formation of a specialized scientific and clinical infrastructure, are identified.