No abstract

Background Magnetic Resonance(MR) guided percutaneous procedures(MRgVABB) have been developed and largely employed to reduce the need of surgical biopsies for suspicious lesions which can be detected only by MR(MR-only lesion). The present study aims to investigate correlation between imaging, histological features of MRgVABB and surgical specimens of MR-only lesions. Methods We retrospectively enrolled 56 patients with a total of 61 lesions. Each finding was defined as Mass-Enhancement(ME) or Non-ME(NME) and classified according to BI-RADS. MRgVABB and surgical data were collected. Concordance between MR, MRgVABB and open biopsy was calculated. Underestimation Rate(UR) of MRgVABB with surgery was obtained. Results B2 and B5b lesions were statistically associated with NME and ME, respectively. No statistical association was found to B3 nor to B5a with radiological features. UR was 10 %; underestimated lesions were strongly associated with the presence of a ME on MR imaging. Moreover, B3 lesions are associated with higher UR. Conclusion Radiological features should influence patient management aiming to construct a correct diagnostic and therapeutic plan. When MR is prescribed for breast cancer staging for ME-MR-only lesions, we suggest surgical open biopsy instead of MRgVABB when upfront surgery is the treatment of choice.

Liver lipoma is a rare benign mesenchymal tumour without malignant degeneration. Lesions may be asymptomatic, nevertheless they may sometimes cause abdominal pain depending upon the size. Usually liver lipomas are an incidental finding during radiological examinations performed for other reasons, and there is no evidence of familiar genetic cluster or predisposing factors but it seems to have a strong association with impaired lipidic profile. In this report, we describe the case of a 72 year old female with a giant liver lipoma observed during an ultrasound examination. The clinical examination was completed with CT and MRI scans. Features of the lesion such as negative attenuation values on multiphasic CT examination and MRI signal drop-out on T2 spectral presaturation with inversion recovery sequences, with no enhancement after administration of contrast medium, are suggestive for this kind of benign neoplasm. The purpose of this report is provide an anthological case of liver lipoma, helping to define the diagnostic features with imaging techniques.

Our study demonstrated that HMCAS obtained with multidetector CT can be detected in more than 70 % of patients with large acute ischaemic lesion and it is an unfavourable prognostic sign.