We report that glycolysis in human quiescent fibroblasts stimulated by serum addition is increased, and that the changes of the metabolic route reflect the activity of the phosphofructokinase. A possible role of fructose-2,6-bisphosphate as a positive modulator of the key enzyme is proposed.Phosphofnctokinase Fructose-2,6_bisphosphate Glycoiysis Human fibroblast

We report that fructose 2,6-bisphosphate (Fru-2,6-Pz) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time-and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed. Human fibroblast Fructose 2,6bisphosphate Glycolysis

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Abstract. In this paper we simulate a Unmanned Aerial Vehicle's (UAV) recognition after a possible case of diffuse damage after a seismic event in the town of Acireale (Sicily, Italy). Given a set of sites (84 relevant buildings) and the range of the UAV, we are able to find the number of vehicles to employ and the shortest survey path. The problem of finding the shortest survey path is an operational research problem called Vehicle Routing Problem (VRP) whose solution is known to be computationally time-consuming. We used the Simulated Annealing (SA) heuristic that is able to provide stable solutions in relatively short computing time. We also examined the distribution of the cost of the solutions varying the depot on a regular grid in order to assess the best area where to execute the survey.

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