The authors describe the case of a 43-year-old man with a right-leg knee amputation performed 14 years prior. He presented to hospital with dyspnea. A pulmonary embolism was detected. A Doppler ultrasound test showed deep vein thrombosis (DVT), which affected the stump of the amputated limb. When a pulmonary embolism is detected in a patient with an amputated lower limb, an exploration of the stump should be performed to rule out this uncommon complication.

survival was 3.73 months (95% CI 2.8-4.2). Factors associated with increased survival included treatment as first-line (p <0.001), type of response (p <0.001) and PD-L1 status (p ¼ 0.0039). Compared with the historical cohort, immunotherapy proved to be superior in terms of OS (p¼ 0.05) but not PFS (p¼ 0.2). Conclusion: Patients who receive immune checkpoint inhibitors as part of their treatment for NSCLC have better OS compared with matched patients treated with standard chemotherapy, regardless of treatment line.