In moderate-to-severe chronic heart failure patients, the 6-min walk test is not related to cardiac function and only moderately related to exercise capacity. Walking performance does not provide prognostic information which can complement or substitute for that provided by peak VO2 or NYHA class. Hence the test is of limited usefulness as a decisional indicator in clinical practice.
Considerable delay in switching to second-line cART may occur despite an observed high rate of failure. Factors including WHO clinical stage and tuberculosis co-infection should be evaluated before starting cART. Toxicity and drug adherence should be monitored to minimize drug substitution in LMIC.
In recent years, both researches and practitioners have devoted attention to environmental sustainability of supply chain (SC), while firms have modified their marketing strategies highlighting green practices in productive and logistic processes among the features of their products. These behaviours move firms to require to their suppliers the adoption of green measures and practices to reduce environmental impacts within the entire SC. This paper presents the results of an exploratory case-based research on the SC of fresh chestnuts aimed to integrate environmental concepts in the value chain approach, with a concurrent evaluation of sustainability improvements and their economic impact. Within the value chain configuration, environmental KPIs are defined for the specific case study and a logistic environmental model is developed. Within the model, an evaluation of carbon footprint for this SC is proposed, along with its possible improvements. Results include the analysis of different improvement scenarios and their comparison.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.