Background: MPV17 is a mitochondrial inner membrane protein with unknown function.Results: Recombinant human MPV17 shows highly regulated channel-forming activity; the mitochondrial membrane potential and the reactive oxygen species formation were elevated in embryonic fibroblasts from Mpv17 Ϫ/Ϫ mice.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.