Erythrokeratoderma are diverse group of genodermatosis affecting keratinization under which, Erythrokeratodermia Variabilis ( EKV) was first described in 1925 by Mendes da Costa. Our patient is a 48 year old male presenting clinically with EKV Mendes Da Costa, hyperkeratotic subtype with the histopathology supportive of the diagnosis. We are reporting for its rarity and due to its late onset in our patient and also for the sporadic nature of this particular case of EKV.

cAse seRIes INTRoDucTIoNFixed drug eruption is a type of cutaneous adverse drug reactions accounting for 4-39% of all drug eruptions worldwide. [1] Paucity of data in Indian population but a systemic review reported its incidence as 20.13% amongst Cutaneous Adverse Drug Reactions. [2,3] Here we present a collection of cases observed in our patients.

Immunotherapy for management of cutaneous wart with measles, mumps and rubella vaccine (MMR) is a promising new modality of management. Evaluation of the same has been done by various studies over the years reporting its effectiveness. A literature search was done using PubMed and google scholar. This short narrative review documents the response rates in various clinical studies done till 2019 which have reported the efficacy of MMR vaccine as an immunotherapeutic agent which ranged from 26-84% graded as complete response which is complete clearance of the treated warts. These studies were performed for evaluating MMR vaccine as single agent or done in comparison with other therapeutic agents. The broad range of responses points to a need of doing further clinical studies which will substantiate the effectiveness of MMR vaccine in the treatment of cutaneous warts.