BbOd transfusion has developed os a clinical nique. Its development has progressed from ignorance to science and from cruelty to civilization over hundreds Of years. Transfusion has mode great contribution {or saving lives ond expanding operation coverage. Blood letting wos Widely practiced for a variety Of conditions from the time Of Hippocrates and yet transfusion Only became a common place theropeutic intervention less thon pears 090. Although the association Of blood with life and vitality was recognized by primitive man, the transfusion Of wos not possible until Hervey described circulation in 1628. transfusion Of blood wos only one of the mo ny scientific competitions in Which thecitizensofFranceondEnglandengogedin 16005. This foundation for transfusion theropy that were built in 100 years later The developrnent Of transfusion medicine started from the attempts to transfuse blood in c nirnols in the 1 71b centu ry and the first fruits were seen in the half of century'