Tumor ganas pankreas pada tahun 2018 menempati urutan ke-8 dari 10 tumor ganas di Amerika dan Asia menjadi benua dengan kasus tumor ganas pankreas tertinggi di seluruh dunia, yaitu sebanyak 214.499 (46,7%) dari 458.918 kasus. Penelitian tentang tumor ganas pankreas di Indonesia masih sangat jarang dilakukan termasuk di Jawa Barat sehingga data epidemiologi masih sangat kurang sedangkan tumor ganas pankreas di dunia menjadi penyakit dengan jumlah kasus kematian tertinggi ke-7. Tujuan penelitian ini adalah untuk mengetahui gambaran tumor ganas kaput pankreas berdasarkan usia, jenis kelamin, gejala klinis, stadium tumor, dan diagnosis histopatologi di Rumah Sakit Umum Pusat (RSUP) Dr. Hasan Sadikin Bandung periode 2015-2019. Penelitian ini merupakan penelitian deskriptif dengan mengambil data sekunder yaitu data rekam medik. Hasil penelitian menunjukkan jumlah kasus tumor ganas kaput pankreas di RSUP Dr.Hasan Sadikin Bandung periode 2015-2019 yang masuk kriteria inklusi 32 kasus (56,25%) dengan kasus terbanyak pada perempuan. Kelompok usia terbanyak terjadi pada usia 50-59 tahun sebanyak 37,5%. Gejala klinis yang paling sering menjadi keluhan utama pasien adalah ikterus sebanyak 43,75%. Pasien paling banyak didiagnosis pada stadium IV sebanyak 37,5%. Diagnosis histopatologi yang paling sering ditemukan adalah Infiltrating Duct Carcinoma yaitu sebanyak 31,23%. Kesimpulan dari penelitian ini adalah tumor ganas kaput pankreas terutama terjadi pada perempuan usia 50-59 tahun dengan gejala klinik terbanyak, yaitu ikterus dan umumnya datang pada stadium IV. Diagnosis histopatologi terbanyak adalah Infiltrating Duct carcinoma.

The freeze-dried soyghurt generally will be last much longer. However, the reduction of L. acidophilus and B. bifidum (LAB) colonies during the freezedrying process could be occurred and it could be minimized by adding inulin as a prebiotic and sucrose as a cryoprotector. This research aimed to determine whether or not the colonies number in freeze-dried soyghurt with the SNI and to analyze the effect of inulin and sucrose addition to the growth of the LAB in the freeze-dried soyghurt. This experimental laboratory study with pretest-posttest design consists of 1 negative control group, 1 group of soyghurt, and 4 groups of soyghurt with the addition of 10% sucrose and 0.5%, 1%, 3%, 5% inulin. The bacterial growth was calculated using the TPC method. All data were tested using the Saphiro Wilk test, followed by the Kruskal Wallis and Mann Whitney Post Hoc test. The conclusion of this research was that the number of colonies in each experimental groups decreased after the freeze-dried process and only the group of soyghurt without any additions did not meet the standard of SNI. Statistical tests showed a significant distinction between groups, giving a conclusion that the addition of inulin and sucrose gave a better incretion of the LAB significantly. 10% sucrose and 3% inulin was the best combination which has 2.34 × 1029 CFU/ml as the highest TPC. It means that the higher of sucrose and inulin addition to the soyghurt, does not guarantee the number of LAB colonies inside will also be higher.

Obesity is a health problem in Indonesia. Data shown by Basic Health Research (Riskesdas) in 2013 described the prevalence of obesity in Indonesia as increasing annually. Obesity becomes a risk factor for many diseases, the example of it is a musculoskeletal disorder in the cause of mobility disorder. Victims of obesity are known to have limited movement and joint range of motion (ROM) reduction caused by mechanical hindrance in joint movement. This research is focusing on discovering the relationship between obesity and hip joint ROM reduction in students at the Faculty of Medicine Jenderal Achmad Yani University. This research is also using a correlation analytical layout with a cross-sectional approach. The research subject is consisting of 20 males and 38 females student members with a body mass index (BMI) of ≥ 25 kg/m2. Anthropometrical data and hip joint ROM are obtained from direct measurement of the subject. The data are descriptively analyzed then continued with Spearman correlation assessment. The result of this research is stating that there is a significant negative correlation between obesity and hip joint ROM flexion, extension, abduction, adduction, and exorotation (p < 0.05), except for hip joint ROM abduction in female (p > 0.05)also a significant positive correlation between obesity and hip joint ROM endorotation (p < 0.05). In conclusion, this research is showing that there are relations between obesity and hip joint ROM reduction in flexion, extension, abduction, adduction, and exorotation movements. Therefore, in a female group, there is no relation between obesity and hip joint ROM reduction in adduction.