This study deals with the landscape evolution reflected in the changes of land cover in the suburban area of Marathon, Attica, Greece. The study was based on remote sensing images covering the time period between 1945 and 2007. Several other types of data were also used, such as a digital terrain model, historical orthophotos, vegetation maps, geological maps, cadastral maps and aerial photos. These types of data were used in order to create the spatial database for the classification/interpretation of land cover and to identify the land cover changes that occurred during the period in question. The results of this study showed significant land cover changes, especially for the land covered by forests and wetlands with a 47% and a 37% decrease, respectively. The spatial arrangement of the development of residential areas was partially predictable, while the occurrence of land cover changes due to retrogressive vegetation succession appeared rather idiosyncratically throughout the area initially covered by forest.