This research addresses the association between attention to science fiction and public opinion of human genome editing (HGE). Using a nationally representative survey, our results show that attention to science fiction is associated with both risk and benefit perception of the technology. In addition, results show that, at higher levels of attention to science fiction, the levels of concern from conservatives (ordinarily predisposed to negative views toward science) and from liberals (ordinarily predisposed to positive views toward science) come closer to being the same. This research contributes to our understanding of debates about controversial science.