Introduction: Nowadays, implant insertion is accompanied by undesired consequences. As surgery techniques become more and more complex, an increase of intra-and post-op complications can be expected. Application of low-level laser (LLL) is one of the conservative approaches to control the complications with any side effects and low treatment costs. The present study aimed to evaluate the effect of 650 nm LLL irradiation on the reduction of complications after advanced implant surgeries. Materials and methods:In this triple-blinded clinical trial, 30 patients aged between 25 to 65 years were in need of bone graft or sinus lift procedure for simultaneously implant insertion. In the LLL treatment group, the surgical site of each implant was treated with 650 nm laser. The same method and duration were applied in the placebo group. The pain levels, facial swelling, and wound healing were evaluated.Results: This study indicated that pain levels were reduced in the laser group (p <0.05). Also, facial swelling in the 3rd and 7th day after the surgery relieved more in laser group. Furthermore, investigation of the surgical site showed a higher level of wound healing in the laser group (p <0.05). Conclusion:Regarding the biological effects of advanced implant surgeries and accompanying complications, adjuvant treatment with a laser could significantly improve wound healing and reduce the severity and duration of pain and swelling.Clinical significance: This clinical trial demonstrates reductions of the level of pain, facial swelling and improvements of wound healing are followed by the use of low-level laser therapy.

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