Introduction: Origanum vulagre L. is known for its abundant essential oil content with monoterpene and sesquiterpene derivatives. Aims: This research aims to gather comprehensive information about oregano and its potential to be developed into a nanotechnology drug delivery system. Methods: Literary studies were conducted using data obtained by searching through online literature sources. Results: Oregano is reported to contain active phytochemicals like esitronellol. In modern scientific literature, its extracts have been reported to have antidiabetic, analgesic, anti-inflammatory, anticancer and other potential properties. Further research needs to be done to ascertain the safety and therapeutic effect of this plant. The development of oregano’s essential oil into nanoparticles in dosage forms can increase its solubility, stability, and pharmacological effects.

Introduction: Some patients with comorbidity such as diabetes are at risk of worsening after being infected with the COVID-19 and they usually adjust their diet during the recovery process. Aim: To explore the use of Stevia rebaudiana leaves as a natural sweetener recommended for COVID-19 patients and the nanoparticle approach of S. rebaudiana extract to improve the efficacy. Methods: Four electronic databases (Google Scholar, PubMed, Scopus, and ScienceDirect) were used with specified inclusion and exclusion criteria set. Results: The glycosides produced by S. rebaudiana are 300 times sweeter than sucrose, low in calories, and can control blood sugar levels and increase insulin secretion. The application of nanoparticles in S. rebaudiana extract is a new step to maximise efficacy, increase stability and solubility. Conclusion: S. rebaudiana can be used as an alternative diet for COVID-19 diabetes patients. The application of the nanoparticles can increase the stability and solubility, thus improving the efficacy.

Introduction: One of plants that may have therapeutic potential is the Cymbopogon schoenanthus (L.) Spreng, also known as camel grass. Aim: This review aims to investigate and gather comprehensive information about camel grass plants and their potential to be developed into a nanotechnology drug delivery system. Methods: This review examined a variety of online literature. Results: It was found that camel grass contains essential oil such as piperitone. Piperitone is efficacious as an antioxidant, antimicrobial and anti-inflammatory, in addition to other properties . The development of camel grass essential oil into lipid-based nanotechnology preparations can improve its bioavailability, solubility, and stability, thereby improving its potential effectiveness.