We explored respiratory symptoms in informal versus formal sector workers, in order to find out if there is rational reason for selective care towards the latters. Methodology:This was a transversal analytic study comparing spirometry parameters of 35 carpenters from informal sector activity to 35 controls from official sector, all males, matched for body surface area, in Douala town in Cameroon, from March to May 2015. We performed spirometries and clinical examinations. We analysed data with spss V.22. Results:The carpenters and the controls showed respectively that : average age was 35 vs 34 years ; average years spent in function : 13 vs 9 years ; systolic blood pressure : 120 vs 115 mmHg (p < 0.05) ; diastolic blood pressure : 79 vs 96 mmHg ; on spirometry, forced vital capacity : 97 vs 92 ; forced expiratory volume per second : 101 vs 96 ; Tiffeneau index : 108 vs 105 ; and peak expiratory flow : 91 vs 87. A negative correlation was found in carpenters between lenght of stay in function in years and peak expiratory flow (R = -0.34 ; p<0.05). Conclusion :The spirometry parameters are more altered in the carpenters of informal sector, compared to controls of formal sector. There are no abnormalities exclusively present in formal sector workers that could justify their selective care. This study highlights the need for a real attention to all workers in terms of preventing their health problems by authorities