Synthesis of N-(CAminobutyl)-16-aza-lPnonadecanelactam and N-(4-Aminobutyl)-17-aza-20-icosanelactam(Desoxoinandenine)
SummaryAccording to Scheme I , the two homologous macrocyclic spermidine derivatives 12 and 23 were synthesized. Key steps in both cases were two different types of ring-enlargement reactions. Compound 12 was identical with a degradation product of the naturally occurring spermidine alkaloids of inandenine-type.
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