IntroductionThymic carcinoma is a rare, invasive mediastinal neoplasm with a tendency to metastasize. They constitute a heterogeneous group of tumors that present differently in terms of both behavior and prognosis.Case reportWe present a case of thymic carcinoma in a 55-year-old male patient known to suffer from Myasthenia gravis, whose chief complaints were fatigability, ptosis and coughing. All electromyography studies were done along with excision biopsy to reach the definitive diagnosis.Results and conclusionThe histopathological diagnosis of Thymic carcinoma-Lymphoepithelial variant was established. Though no definite staging system exists for the thymic carcinoma, prognosis of the patient was ascertained by using Weissferdt-Moran system, Masaoka and Tsuchiya TNM staging systems. Involvement of the pleural and the pericardial structures leads to poor prognosis, though no distant metastases or lymph nodal metastasis were evident.
Introduction: Gallbladder stones are commonest disorder among gall bladder lesions and are usually asymptomatic. Its frequency in cholecystectomy specimens is not clear. The aim of this study was to report the morphological variants and frequency of different lesions in cholecystectomy specimens. Objective: To study the various histopathological spectrum of gall bladder lesions. Materials and Methods: In present study we have studied total 141 cases of gall bladder lesion during the period of 6 months from April 2017 to October 2017 in the Dept. of Pathology at Adesh Institute of Medical Sciences and Research, Bathinda. Results: Benign lesions of gall bladder outnumbered the malignant ones with non-neoplastic lesions accounting for 93.6% (132 cases) with chronic calculous cholecystitis contributing the majority of the non-neoplastic lesions (49.64%) followed by cholesterolosis (22.69%), acalculous cholecystitis (4.96%), followed by gangrenous and xanthogranulomatous cholecystitis. Females were predominantly affected in the present study with total 107 cases out of 141 cases-75.8% cases. Most of the non-neoplastic lesions of the gall bladder lesions are common in 3rd, 4th and 5th decades of life. Neoplastic lesions of the gall bladder were common in 5th, 6th and 7th decades of life. Out of 141 cases 5 cases are of adenocarcinoma of gall bladder-3.5% of all cases. The mean age of patient with adenocarcinoma of gall bladder is 60.8 years. Conclusion: Gall bladder lesions were common indication for surgical intervention and pathological evaluation. Most of them were inflammatory lesions with cholelithiasis, however thorough examination is important as these lesions may progress to fatal malignancies.
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