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Since 2005, Makerere University and the University of Dar es Salaaam have taken definitive steps toward the development and utilization of iLabs. This chapter presents the iLabs experiences of the two East African universities. The experiences presented here are characterized by: institutionalization of developer teams, development of ELVIS-based iLabs, staff & student exchanges, and utilization of iLabs to support curricula. The two universities have also undertaken to setup iLabs communities at peer universities and other higher institutions of learning in East Africa.