Background: Till date hysterosalpingography (HSG) remains the first-line method to detect tubal patency and to find out any uterine abnormalities in infertile female while diagnostic hysterolaparoscopy (DHL)  is considered to be the gold standard method, it is during last decades only that saline infusion sonography (SIS)/ sonohysterography (SHG) has emerged as an efficacious method of checking tubal patency and uterine anatomy as well. The present study aims to compare all three methods viz- SIS, HSG and DHL and to evaluate the correlation between these methods.Methods: 98 infertile females of age group 18-35 years with normal Hormonal profile without any male factor infertility, were prospectively selected from the outpatient department of obstetrics and gynecology, GMH Rewa, Madhya Pradesh over one year from 1st August 2016 to 31st July 2017.Results: Diagnostic accuracy (sensitivity and specificity) of SIS was found to be more than HSG for both tubal patency and uterine abnormalities detection. SIS has less numbers of false positive and false negative rates as compared to HSG. DHL was found to be much superior to both SIS and HSG, also detected additional findings in multiple sites like pelvis, tubes and the uterus on the same setting which were missed on SIS and HSG.Conclusions: SIS may replace HSG as a first step screening method for tubal patency detection, as it has more diagnostic accuracy than HSG and better correlation with DHL and has many advantages and minimal disadvantages as compared to HSG.

Background: Abnormal uterine bleeding (AUB) is a very common, challenging gynaecological problem in all age group women. Neoplastic lesions are responsible for very less number of cases but they should be diagnosed early. Endometrial biopsy is necessary for histopathological diagnosis of endometrial lesions and to rule out any malignancy. In present study, we evaluated histopathological pattern of endometrium and different clinical parameters in AUB patients.Methods: A retrospective observational study done in Obstetrics and Gynecology department of SSMC Rewa, Madhya Pradesh in 2 year from 1st October 2017 to 30th September 2019. AUB patients who fulfilled inclusion criteria were included in study. All data were collected from department records in predesigned proforma and statistically analyzed by statistical package for the Social sciences (SPSS) version 20.Results: Total 366 AUB patients were included in study; most frequent clinical presentation was HMB (56%). Mostly patient’s age ranged from 24-84 years, belonged to 41-50 years age group (44%), multiparous (78%), and premenopausal (53%). On histopathological evaluation of endometrium most commonly nonneoplastic lesions (75%) were seen, out of which proliferative phase endometrium was most frequent. Neoplastic lesions were seen in 25% cases. Out of which benign lesions were noted in 7%, premalignant in 17.3% and malignant in 1% (all in >45 year patients).Conclusions: Endometrial biopsy should be done in all AUB patients >45 years and in selected premenopausal in order to get early diagnosis, to rule out malignancy and to help in management. Endometrial biopsy should be considered as first diagnostic modality.