Supplementary Information ExperimentalAll the Reagents and solvents of analytical grade were used as received unless otherwise stated. 1, 10-Phenanthroline monohydrate (phen), 2,2'-bipyridine (bpy),4,4'-dimethyl-2,2'-bipyridine (dmb), and 4,4'-dimethyl-1,10 orthophenonthroline (dmp) were procured from Merck. Calf thymus DNA (CT-DNA) was purchased from Aldrich, Super coiled pBR322 plasmid DNA (stored at 20ºC) from Fermentas Life Sciences and was utilized as it is. Agarose gel was bought from Genei. Ultrapure Milli-Q water (18.2mX) was used in all experiments.The binding affinity of metal complex for CT-DNA was calculated in tris (hydroxymethyl) amino methane, Tris-HCl buffer (5 m.mol Tris-HCl, 50 mM NaCl, pH 7.2). The DNA, free of protein was observed at an absorbance of 260 and 280 nm and a concentration of DNA per nucleotide at a molar extinction Coefficient of 6600 M -1 cm -1 was determined spectrophotometrically 1,2 . Stock solutions of DNA were kept at 40ºC and were put to use in less than four days. The stock solutions

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