The objective of this study is to synthesize zinc oxide nanostructures with the most practical ways by using Ficus Religiosa leaves extract and characterize the nanostructures. ZnO nanoparticles were synthesized using Zinc Nitrate (Zn(NO 3 ) 2 ) as a precursor and Ficus Religiosa leaves extract solvent and distilled water were used as medium. ZnO nanoparticles were characterized by using XRD, UVVisible spectroscopy, EDX and SEM, FTIR. Result of EDX characterization shows that the ZnO nanoparticles has good purity with (Zinc content of-72.48% and; Oxygen content of-27.52%). XRD result spectrum displays mainly oxygen and zinc peaks, which indicate the crystallinity in nature as exhibited. SEM micrographs shows that synthesized ZnO have a cubical structure. The obtained ZnO nanoparticles are homogenous and consistent in size which corresponds to the XRD result that exhibit good crystallinity.