The article examines the regions of the North Caucasus in the context of the implementation of cluster projects. The functions and possibilities of clustering, the versatility of approaches to its definition in domestic and foreign publications are considered. Favorable preconditions for the formation of agro-industrial clusters in combination with agritourism (favorable natural and climatic conditions, operating agro-holdings, significant labor resources, rich cultural and historical heritage, etc.), as well as constraining factors (lack of a unified mechanism for the formation of regional agro-industrial clusters, insufficient activity of the business community in terms of generating ideas and implementing initiative projects, weak involvement of the population in dialogue with the business community and government authorities, etc.). A model of an interregional agro-industrial cluster has been proposed, the core of which will be agricultural holdings operating in the north-east of the Caucasus.