Fused pyrimidine derivativesFused pyrimidine derivatives R 0515 Novel High Energy Intermediate Analogues with Triazasterol-Related Structures as Potential Inhibitors of the Ergosterol Biosynthesis. Part 2. Optimization of the Synthesis of 1,6,7,11b-Tetrahydro-2H-pyrimido[4,3-a] Isoquinolin-4-amines as Parent Compounds of Novel 8,13,15-Triazasteroids. -The desired products such as (XI) and (XII) and the intermediates (VI) only show weak inhibitory activity in an antifungal assay. -(GOESSNITZER*, E.; PUNKENHOFER, A.; Monatsh. Chem. 134 (2003) 6, 909-927; Inst. Pharm. Chem., Karl-Franzens-Univ., A-8010 Graz, Austria; Eng.) -K. Schneider 38-138
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