Tratamiento con células madre en gastroenterología y hepatología ResumenLas células madre están presentes en la mayoría de los tejidos del organismo, permitiendo su renovación perió-dica y su regeneración en caso de producirse un daño tisular. Debido a su capacidad de autorrenovación y de diferenciación en diversos tipos celulares maduros, se están estudiando para el tratamiento de diferentes enfermedades del aparato digestivo, como la enfermedad inflamatoria intestinal, la celiaquía y en el fallo hepático. En esta revisión se incluyen resultados sobre el beneficio de su posible aplicación terapéutica en el campo de la gastroenterología y hepatología, a pesar de que se necesitan muchos más estudios para la comprensión de la biología de las células madre y de su discutida relación con el proceso de carcinogénesis. AbstractStem cells are present in the most human tissues. They have the capabilities of self-renewal and differentiation, allowing the regeneration of a tissue in case of damage. Due to those properties, stem cells have been studied as treatment of numerous gastrointestinal and liver diseases, i.e., inflammatory bowel disease, celiac disease and liver failure. In this review we present results of therapeutic applications of stem cells in fields of gastroenterology and hepatology, even though further studies are needed to better understand biology of stem cells and their controversial role in the carcinogenesis process.
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