Objective To study the association between antenatal umbilical coiling index (aUCI) and perinatal outcome. Methods 600 primigravidas with uncomplicated singleton pregnancies had an ultrasonography between 18 and 22 weeks of gestation for aUCI by colour Doppler. The aUCI was calculated as the reciprocal of the distance between a pair of coils. It was then correlated with the following pregnancy outcomes: birth weight, mode of delivery, meconium staining of liquor, Apgar scores and gestational age. The results were statistically analysed by v 2 -test. Results The mean aUCI was 0.41. Undercoiling was associated with spontaneous preterm delivery (47.87 %), low Apgar score (52.13 %), LBW (52.59 %), FGR (21.28 %) and NICU admission (76.34 %). Overcoiling was associated with preterm deliveries (65.38 %), increased caesarean sections (61.54 %), meconium staining of liquor (67.31 %), low Apgar score (63.46 %) and NICU admission (72.55 %). There was a positive strong correlation between aUCI and birth weight (r = ?0.426) Conclusions Abnormal coiling is strongly correlated with low birth weight.

Early pregnancy failure a b s t r a c tBackground: Nearly 20% of all confirmed pregnancies end in spontaneous abortion. Misoprostol's use in early pregnancy failure is varied and dose and route are not well established. The aim of this study was to compare the efficacy and the side effects of different regimes of misoprostol in causing expulsion of products of conception in early pregnancy failure.Method: Women patients with an ultrasound diagnosis of early pregnancy failure, less than 12 weeks gestation were divided into two, Group-A: tab. Misoprostol 800 mcg 6 hourly vaginally, upto 3 doses. Group-B tablet misoprostol 600 mcg 6 hourly, sublingually for 3 doses. All observations were noted and statistical analyzed.Results: Mean gestational age was 7.93 weeks. Mean induction abortion interval 18.183 h.Women patients with less than six weeks gestational age had least mean inductionabortion interval time, 15.75 ± 2.82 h in vaginal group but was highest in sublingual group 22 ± 2 h and 18.43 h in overall (P ¼ 0.02). Though after 8 weeks, both routes were equally effective. Mean dose required in group-A was 20044 mcg and in group-B was 1564 mcg (P < 0.001). Efficacy of protocol was 88.89% in group-A and 92.85% in group-B. Conclusion:Both regimes had comparable efficacy, acceptability (90%) and side effects. In women patients less than six weeks period of gestation, the vaginal (800 mcg) route was distinctly superior, in women patients with 6e8 weeks the sublingual (600 mcg) route was more advantageous. The correct dose must be used for the route chosen. The route of administration should be decided in accordance with the preference of the patient and the clinical situation.© 2014, Armed Forces Medical Services (AFMS). All rights reserved.* Corresponding author. Tel.: þ91 (0)9828025302 (mobile). E-mail address: hoojasjaipur@gmail.com (N. Hooja).Available online at www.sciencedirect.com ScienceDirect journal homepage: www .e lsev ie r. co m/ lo cate/ mj afi m e d i c a l j o u r n a l a r m e d f o r c e s i n d i a 7 0 ( 2 0 1 4 ) 3 6 0 e3 6 3 http://dx

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LLETZ is a simple, outpatient means of removing the transformation Zone or morbidity to the patient. The aim of our study was to evaluate the therapeutic effectiveness of LLETZ in management of cervical lesions. This prospective study was conducted at Department obstetrics & Gynecology Zenana Hospital, SMS Medical College, Jaipur from December 2014 to June 2015. The study includes all patients who attended colposcopy clinic with complaints of persistent leucorrhea, postcoital bleeding, intermenstrual bleeding and postmenopausal bleeding. We had 29 cases of chronic endocervicitis, 27 showed an inflammatory smear while 2 showed LGSIL. 3 patients showing HGSIL on pap smear showed CIN -I on histopathology. This was false positive of Pap smear (6%). 1 patient of invasive squamous cell carcinoma showed HGSIL on pap smear. Thus LEEP was useful in diagnosing a case of invasive carcinoma which would have been missed with Pap smear alone. Also 3 patients of CIN -II on biopsy had inflammatory (1) and LGSIL (2) on pap smear. LEEP (Loop Electrosurgical Excision Procedure) is a feasible management strategy for cervical lesions especially in developing countries like India where incidence of cervical carcinoma remains high because of ineffective screening and poor patient compliance for follow up.

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