This review of orofacial malformations describes clefting anomalies that emanate from the mouth and lips. As the causes of orofacial clefts are better understood, it is becoming clear that a complex interplay between genetic and environmental variables causes these clefts. Future study of orofacial clefts will require increasingly sophisticated methods of elucidating these subtle interactions.

Selection of plate size, miniplate versus reconstruction plate, does not appear to affect the overall rate of complications in free fibular reconstruction of the mandible.