chemotherapeutic care for the treatment of colorectal cancer (CRC) in the last decade. CAPOX treatment was proven to be equivalent or non-inferior to standard regimens like FOLFOX and FOLFRI in the treatment of advanced and metastatic CRC (Pectasides et al., 2015; Guo et al., 2016; Sobrero et al., 2018) and preferred over its counterparts due to convenience in administration and easy management. (Wehler et al., 2012) However, CAPOX treatment was associated with several dose-limiting haematological and non-haematological toxicities (Mullally et al., 2018; Baird et al., 2011) and patients show high inter-individual variation to its toxicity profile.