Two experiments were conducted at South Valley Farm Research Station, Toshka Region, Agriculture Research Center during 2018 and 2019 seasons. To study the effect of different proline concentrations and planting methods and their interaction on the productivity of sesame grown under a drip irrigation system. The experiment was carried out in (RCBD) using strip-plot arrangement with three replications, The two planting methods (terraces and rows) were assigned horizontally while, the four proline concentrations (0.0, 25, 50 and 75 ppm) were allocated vertically. The result showed that the studied planting methods had a significant impact on plant height, frouting zone length, number frouting nods plant -1 , number of seeds capsule -1 , weight of seeds plant -1 , seed yield, oil %, and oil yield traits in both seasons in favor of rows planting methods in most traits except oil percentage in favor of terraces planting methods and proline 50 ppm sprayed at 45 and 60 days after planting DAP recorded significantly higher seed yield (579.02 and 586.99 kg fed -1 ) and yield attributes in both seasons, except plant height was not significant in the two seasons, frouting zone and oil percentage in the second season. The interaction between planting methods and proline concentrations had a significant impact on all traits in both seasons, except plant height and number of seeds capsule -1 in the 2 nd season and frouting zone in both seasons. Consequently, the maximum average values of oil yield (294.62 and 302.98 kg fed -1 ) in the 1 st and 2 nd seasons, respectively.