Retinol is lipid soluble vitamin widely used during pregnancy as a food supplement.The study has been conducted in Animal House/Faculty of Sciences/University of Kufa between December 2021 and February 2022, fifteen female Albino Rats are used. The present study has been intended to show the histolopathologiacl effects of retinol on blastocyst implantation in female Albino Rats. The females Rats are randomly divided into three main groups, comprising five rats for each group. The control group is given orally injection of physiological normal saline and the second and third group are given orally injection of retinol doses ten, twenty μcg/kg/day respectively for seven days from the first day to the end of experimental allocated for each female.The rats are sacrificed in 7 th (dpc) to study the implantation of embryos in decidual tissues. Retinol doses ten, twenty μcg/kg/day caused macroscopic malformations in embryos of female rats compare to control group. The histopathlogical study of female rats embryos treated with ten, twenty μcg/kg/day of retinol have shown deformations of decidual tissues zonation.In conclusion; retinol caused malformations of embryos in 7 th (dpc) and histopathlogical effects in decidual tissue zonations of blastocyst.
Vitamin A is lipid soluble vitamin widely used during pregnancy as a food supplement. The study has been conducted in Animal House/Faculty of Sciences/University of Kufa between December 2021 and February 2022, thirty female Albino Rats are used. The present study has been intended to show the teratogenic effects of Vitamin A on embryos in female Albino Rats. The females Rats are randomly divided into four main groups,The first and second control groups are given orally injection of physiological normal saline and the third group 15th (dpc) are given orally injection of vitamin A doses ten, twenty μcg/kg/day respectively for fifteen days from the first day to the end of experimental allocated for each female. The fouth group 20 th (dpc) are given orally injection of vitamin A doses ten, twenty μcg/kg/day respectively for tewnty days from the first day to the end of experimental allocated for each female. The rats are sacrificed in 15,20 th (dpc) to study the teratogenic effects on embryonic bodies.Retinol doses ten, twenty μcg/kg/day caused macroscopic malformations in embryos of female rats compare to control group.In conclusion; Vitamin A caused malformations of embryos in 15 th and 20 th (dpc).
The purpose of the experiment is an investigate the association of walnut oil with lipid profiles, glucose as well as total proteins and assessment its side effect on some sensitive organs such as the liver and spleen tissues. The experiment divided into two main groups are treated group with walnut oil and the control group, where the former divided into two subgroups 0.25 and 0.5 ml of oil per each. We found a statistically non-significant difference between treated and control groups (for total protein, lipid profile, and glucose). There was no change in total protein, but cholesterol decreased by 0.25 ml but a little increased by 0.5 ml. HDL was increased for the treated group. While on 0.25 ml LDL decreased in treated animals, on another hand no change for 0.5 ml. Also, no change for VLDL between treated and control. The only triglyceride was increased but non-significant for the treated group compared with the control. Both doses decreased in treated animals for glucose. We also found an increase in whole-body weight and on sensitive organs such as the liver and spleen. Even no change in a histological study for the mentioned organs. The conclusion: By walnut oil, all parameters have changed despite the treated group was normal without any induced diseases. So, recommended the researchers induce the disorders in the liver and assessment the extracted oil on the lipid profile.
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