A dihydroxybenzoic acid analog used as a flavoring agent is vanillic acid (4hydroxy-3-methoxybenzoic acid). It's a form of vanillin that has been oxidized. It's also a step in the process of making vanillin from Ferulic Acid. Vanillic acid has seen a lot of press because of its many uses in the cosmetics, fruit, flavorings, cigarettes,alcohols, drinks, and polymer sectors. It's said to have effective antioxidant, anti-inflammatory, and neuroprotective properties. The pharmacological impact on oxidative stress-induced neuro-degeneration, on the other hand, have not been thoroughly examined. The pharmacological properties of vanillic Acid lead to its possible use in the treatment of various diseases. Keywords: Vanillic acid, Pharmacological Potential, wound healing, Antioxidants

DEET based mosquito repellents were found to be comparatively harmful to the person suffering from urea cycle disorders such as ornithine transcarbamylase (OTD) deficiency and, are therefore, contraindicated in individuals. These situations lead to the budding necessity of natural mosquito repellents which will have inexpensive, effectual, non-toxic, environment-friendly, and biodegradable attributes. Inspired from the upcoming global need, a carbopol 940 based mosquito repellant gel formulation was prepared from the essential oils of Cymbopogon nardus, Murraya Koenigii, Cymbopogon citratus, Tridax procumbens, Eucalyptus globules, and Azadirachta indica, and further evaluating them for their appearance, pH, viscosity, spreadability, extrudability, swelling index, and accelerated studies. The mosquito repellent potential was evaluated and simultaneously compared with the positive control (Odomos®). In several developing nations, where the majority of the people do not have access to mosquito net, high-cost mosquito repellant creams, and miscellaneous physical methods, this gel formulation may be an effective, inexpensive, and easily accessible way to prevent mosquito-borne diseases, like malaria, dengue, etc. in the lower sections of the society. Keywords: Mosquito, Repellent, Malaria, Gel, Formulation, DEET.

Montelukastsodium is a selective, orally acting leukotriene receptor antagonist that is used for the treatment of asthma and seasonal allergic rhinitis. In addition, patients with asthma need fast and immediate action of drug and avoidance of water is also desirable. Further, chewable tablets are beneficial for patients having difficulty in swallowing. The objective of the present study was to develop chewable tablets containing different compositions of ingredients by using direct compression method. Microcrystalline cellulose, mannitol, magnesium stearate, cross povidone and aspartame were used in the formulation in different concentrations. The prepared tablets were evaluated for various parameters like weight variation, thickness, friability, drug content, and in-vitro drug release. The in-vitro release study of formulation F7 was found to show 98% drug release in 30 minutes and stability studies showed no significant changes.

During the puberty, imbalance of internal constituents and hormonal balance may cause many skin problems. Acne is found as most common skin problem. Face and neck are the major affected area. Preventive approaches involve removal of oil from the face. Proper cleaning and washing require for this purpose. Various researches have been proved utility of herbal based formulations for cleaning purpose which also removes excess oil; considering this fact present work was intended to prepare a face wash gel using Psidium guajava seed extract with antioxidant and antibacterial properties. Prepared gel was evaluated for various quality control parameters like; spreadability, pH, consistency and grittiness, etc. The results of quality control parameters were found to be satisfactory. Keywords: Acne, Gel, Antimicrobial, Psidium guajava, Face-wash

Spices, food additives, which are the main sources of taste, colour, and perfume in foods and beverages, are becoming more and more important due to their wide range of applications. Spices are consumed as food additives to improve the sensory quality of foods. Traditional systems of medicine have employed spices for centuries since they have been known to have physiological effects that are good for human health. In the past few decades, pioneering experimental research involving both animal studies and human trials has been carried out which proved thatspices have therapeutic effects. The benefits of spices’ like nutritional, antioxidant, anti-microbial, and therapeutic characteristics are many. These potentials activities of spices also adds up with their far reaching nutraceutical values. The primary health challenges facing humanity today are diabetes, cardio-vascular illnesses, arthritis, and cancer. Thus the anti-diabetic, anti-hypercholesterolemic, anti-carcinogenic, digestive stimulant action, antilithogenic property, anti-inflammatory property, antimutagenic, and anticarcinogenicand anti-inflammatory actions of spices are of utmost importance in the current situation. The present chapter deals with review of the nutraceutical and health benefits of various spices used in daily diet.