A pot experiment was conducted to determine the potential of AM fungi in phytoremediation of heavy metals and its effect on yield of wheat crop. The experiment was conducted in CR Design with four replications during rabi 2012-13. Data showed no increase in grain and shoot yields by AMF inoculation with Zn, Cu, Fe, Mn at different levels but increased root yield, plant height, spike length and hundred grains weight of wheat as compared with un-inoculated crop. Post-harvest soil Zn, Cu, Fe and Mn contents of 2, 4.4, 2.8 and 2.9 mg•kg −1 , respectively were maximum in un-inoculated plants treated with Zn, Cu, Fe, Mn at triple of recommended level. No increases in plant P, N, Zn, Cu, Fe and Mn uptakes were observed by the inoculation of AMF when compared with uninoculated crop. Maximum plant Zn, Cu, Fe and Mn uptakes of 160.5, 206, 1914.6 and 2653 g•ha −1 , respectively were recorded in uninoculated plants applied with Zn, Cu, Fe, Mn at triple of recommended levels. Wheat roots infection intensity by AMF increased with higher AMF soil spores density. Results suggest the potential of phytoremediation of contaminated soil to be improved by the inoculation of crops with AMF.